Dopaminergic Modulation of Working Memory and Cognitive Flexibility in a Zebrafish Model of Aging-Related Cognitive Decline
M. Cleal, B. D. Fontana, M. Double, R. Mezbrovschi, L. Parcell, E. S. Redhead, M. O. Parker
This study examines age-related cognitive decline in zebrafish and finds that dopamine receptor agonist treatment improves working memory in aging fish but causes downregulation of dat expression at higher doses.
bioRxiv · Jun 5, 2020Animal Behavior & Cognition