Author

L. Pierik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:statistical model· 2 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. R. A. Anderson· 2 shared J. West· 2 shared A. Marusyk· 1 shared B. Desai· 1 shared C. Armagost· 1 shared M. Robertson-Tessi· 1 shared M. Strobl· 1 shared P. McDonald· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersCancer Biology

A. R. A. Anderson

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2 papers

Recent·Most cited

Second-order effects of chemotherapy pharmacodynamics and pharmacokinetics on tumor regression and cachexia

L. Pierik, P. McDonald, A. R. A. Anderson, J. West

This study examines how varying chemotherapy dose schedules affect tumor regression and cachexia, finding that high variance schedules can improve outcomes without increasing total dose.

bioRxiv · Jun 14, 2023Cancer Biology

Antifragile therapy

J. West, B. Desai, M. Strobl, L. Pierik, R. Vander Velde, C. Armagost, R. Miles, M. Robertson-Tessi, A. Marusyk, A. R. A. Anderson

This paper introduces a mathematical framework to quantify cancer cell line fragility or antifragility to treatment variability and applies it to treatment resistance and collateral sensitivity.

bioRxiv · Oct 8, 2020 · PreprintCancer Biology