Author

L. Quadros Barse

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Biochemistry· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

J. E. Bandow· 2 shared L. I. Leichert· 2 shared N. Lupilov· 2 shared A. M. Imann· 1 shared A. Ulfig· 1 shared J. Yoo· 1 shared K. Becker· 1 shared M. Fischer· 1 shared

Activity by Year

2024-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

J. E. Bandow

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Comparison of the mechanism of antimicrobial action of the gold(I) compound auranofin in Gram-positive and Gram-negative bacteria

L. Quadros Barse, A. Ulfig, M. Varatnitskaya, M. Vazquez-Hernandez, J. Yoo, A. M. Imann, N. Lupilov, K. Becker, M. Fischer, J. E. Bandow, L. I. Leichert

This paper investigates how auranofin affects Gram-positive and Gram-negative bacteria, finding that Gram-negative bacteria are more resistant due to efflux systems and glutathione levels.

Microbiology Spectrum · Nov 5, 2024Peer-reviewedBiochemistry

Auranofin induces disulfide bond-mimicking S-Au-S bonds in protein thiol pairs

L. Quadros Barse, P. Duchting, N. Lupilov, J. E. Bandow, U. Kramer, L. I. Leichert

This study shows auranofin forms S-Au-S bonds between cysteine thiols in proteins, independent of thioredoxin reductase, suggesting a new mechanism for its antibacterial activity.

bioRxiv · Jan 15, 2024 · PreprintBiochemistry