Author

L. R. Barrows

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

V. Planelles· 2 shared A. L. Lim· 1 shared A. M. Spivak· 1 shared C. D. Pond· 1 shared E. C. Larson· 1 shared E. T. Larragoite· 1 shared L. J. Martins· 1 shared L. L. Martins· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

V. Planelles

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2 papers

Recent·Most cited

Histone deacetylase inhibition reduces deleterious cytokine release induced by ingenol stimulation

E. T. Larragoite, R. A. Nell, L. J. Martins, L. R. Barrows, V. Planelles, A. M. Spivak

This study identifies HDAC inhibitors that reduce pro-inflammatory cytokine secretion during HIV-1 latency reversal without reactivating the virus.

bioRxiv · Sep 24, 2021Microbiology

HIV-1 provirus transcription and translation in macrophages differs from macrophages containing pre-integrated cDNA complexes and requires E2F transcriptional programs

A. L. Lim, P. Moos, C. D. Pond, E. C. Larson, L. L. Martins, M. A. Szaniawski, V. Planelles, L. R. Barrows

The paper compares HIV-1 transcription from pre-integrated cDNA and integrated provirus in macrophages using scRNA-seq, finding that provirus transcription correlates with viral protein production and E2F transcriptional programs.

bioRxiv · Apr 21, 2021Microbiology