Author

L. R. Kolich

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Approach:deep learning· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Assay:structural biology· 1

Frequent Co-Authors

D. C. Ekiert· 2 shared G. Bhabha· 2 shared M. R. MacRae· 2 shared N. Coudray· 2 shared C. Lam· 1 shared D. Puvanendran· 1 shared E. M. Teran· 1 shared G. L. Isom· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersBiophysics

D. C. Ekiert

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2 papers

Recent·Most cited

Protein-protein interactions in the Mla lipid transport system probed by computational structure prediction and deep mutational scanning

M. R. MacRae, D. Puvanendran, M. A. B. Haase, N. Coudray, L. R. Kolich, C. Lam, M. Baek, G. Bhabha, D. C. Ekiert

The paper maps protein-protein interactions in the Mla lipid transport system using deep mutational scanning and AlphaFold2 structure predictions, revealing overlapping binding sites on MlaC.

bioRxiv · Dec 9, 2022Biophysics

Structure of MlaFB uncovers novel mechanisms of ABC transporter regulation

L. R. Kolich, Y.-T. Chang, N. Coudray, S. I. Giacometti, M. R. MacRae, G. L. Isom, E. M. Teran, G. Bhabha, D. C. Ekiert

The paper reports the X-ray structure of MlaFB from E. coli, revealing how the regulatory subunit MlaB stabilizes the nucleotide binding domain and how the C-terminal tail of MlaF mediates dimerization and complex assembly.

bioRxiv · Apr 27, 2020Microbiology