Cancer BiologybioRxiv
Interfering with MIF-CD74 signalling on macrophages and dendritic cells with a peptide-based approach restores the immune response against metastatic melanoma.
C. R. Figueiredo, R. A. Azevedo, S. Mousdell…·A. Mielgo
This study shows that a peptide-based therapy targeting the MIF-CD74 pathway in macrophages and dendritic cells can restore anti-tumour immunity in metastatic melanoma.
DOI 10.3389/fimmu.2018.01132