Cryo-EM Structure of Native Human Uromodulin, a Zona Pellucida Module Polymer
A. Stsiapanava, C. Xu, M. Brunati, S. Zamora-Caballero, C. Schaeffer, L. Han, M. Carroni, S. Yasumasu, L. Rampoldi, B. Wu, L. Jovine
The paper reports the cryo-EM structure of native human uromodulin, revealing its filamentous conformation and mechanism of bacterial binding.
bioRxiv · May 28, 2020Biophysics