WNT4 regulates cellular metabolism via intracellular activity at the mitochondria in breast and gynecologic cancers
J. L. Sottnik, M. T. Shackleford, F. R. Villagomez, S. Bahnassy, S. Oesterreich, J. Hu, Z. Madak-Erdogan, R. B. Riggins, B. R. Corr, L. S. Cook, L. S. Trevino, B. G. Bitler, M. J. Sikora
This study identifies WNT4's role in regulating cancer metabolism through mitochondrial intracellular signaling in breast and gynecologic cancers, linking genetic variants to metabolic remodeling.
bioRxiv · Jul 15, 2022Cancer Biology