Transposon mutagenesis identifies cooperating genetic drivers during keratinocyte transformation and cutaneous squamous cell carcinoma progression
A. Aiderus, J. Y. Newberg, L. Guzman-Rojas, A. M. Contreras-Sandoval, A. L. Meshey, D. J. Jones, F. Amaya-Manzanares, R. Rangel, J. M. Ward, S. C. Lee, K. H.-K. Ban, K. Rogers, S. M. Rogers, L. Selvanesan, L. A. McNoe, , M. B. Mann
This study uses transposon mutagenesis to identify genetic drivers of keratinocyte transformation and cutaneous squamous cell carcinoma progression in vivo, revealing both known and novel genes involved in the disease.
bioRxiv · Dec 24, 2019Cancer Biology