Author

L. Sheffield

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Immunology· 1

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Assay:bulk RNA-seq· 1 Organism:Drosophila· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. Evans· 1 shared C. Goltz· 1 shared E. Hagedorn· 1 shared J. L. Fierst· 1 shared M. Delfeld· 1 shared N. Sciambra· 1 shared S. Chtarbanova· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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7 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Evans

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1 paper

Recent·Most cited

Age-dependent impairment of disease tolerance is associated with a robust transcriptional response following RNA virus infection in Drosophila

L. Sheffield, N. Sciambra, A. Evans, E. Hagedorn, M. Delfeld, C. Goltz, J. L. Fierst, S. Chtarbanova

This study shows that aged Drosophila have impaired disease tolerance to RNA virus infection, marked by stronger transcriptional responses and altered gene regulation related to apoptosis and mitochondrial function.

bioRxiv · Sep 21, 2020Immunology