Author

L. Timple

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

C. P. Doyle· 3 shared G. R. Hammond· 3 shared A. Rectenwald· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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3 shared papersCell Biology

C. P. Doyle

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3 papers

Recent·Most cited

OSBP is a major determinant of Golgi phosphatidylinositol 4-phosphate homeostasis

C. P. Doyle, L. Timple, G. R. Hammond

The paper investigates OSBP's role in maintaining Golgi PI4P homeostasis through genetic manipulations and finds OSBP regulates PI4P levels at ER:Golgi contact sites.

bioRxiv · Dec 21, 2023Cell Biology

Orthogonal targeting of SAC1 to mitochondria implicates ORP2 as a major player in PM PI4P turnover

C. P. Doyle, A. Rectenwald, L. Timple, G. R. Hammond

The paper investigates PM PI4P turnover by targeting SAC1 to mitochondria, finding that ORP2 significantly affects PM PI4P levels independently of contact sites.

bioRxiv · Aug 28, 2023Cell Biology

Depletion of Plasma Membrane PI4P by ORP5 Requires Hydrolysis by SAC1 in Acceptor Membranes

C. P. Doyle, L. Timple, G. R. Hammond

The authors retract their paper due to an incorrect conclusion about ORP5's role in PI4P depletion, finding SAC1 targeting alone suffices.

bioRxiv · Aug 4, 2022 · PreprintCell Biology