Microniches in biofilm depth are hot-spots for antibiotic resistance acquisition in response to in situ stress
L. Tlili, M.-C. Ploy, S. Da Re
The paper shows that a small percentage of bacteria in biofilm depth induce SOS response and integrase expression, promoting antibiotic resistance acquisition through endogenous stress.
bioRxiv · Nov 3, 2021 · PreprintMicrobiology