Temporal Application of Lysyl Oxidase during Hierarchical Collagen Fiber Formation Differentially Effects Mechanics in Engineered Tissues
M. Bates, L. Troop, M. E. Brown, J. L. Puetzer
This study evaluates the effect of LOX treatment timing on collagen fiber formation and mechanics in engineered tissues, finding that LOXL2 supplementation at 4 weeks improves crosslinking and tissue strength.
bioRxiv · Oct 18, 2022Bioengineering