Selectivity and engineering of the sialoglycan-binding spectrum in Siglec-like adhesins
B. Bensing, L. V. Loukachevitch, R. Agarwal, I. Yamakawa, K. Luong, A. Hadadianpour, H. Yu, K. Fialkowski, M. Castro, Z. Wawrzak, X. Chen, J. Baudry, J. Smith, P. Sullam, T. M. Iverson
This study identifies determinants of sialoglycan-binding selectivity in Siglec-like adhesins and creates engineered binding proteins for specific glycan recognition.
bioRxiv · Oct 7, 2019 · PreprintBiochemistry