Author

L. van Hooren

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1

Frequent Co-Authors

A. Dimberg· 1 shared A. S. Jakola· 1 shared A. Smits· 1 shared A. Vaccaro· 1 shared H. Huang· 1 shared I. Pietilä· 1 shared J. Lau· 1 shared K. Vazaios· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

A. Dimberg

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1 paper

Recent·Most cited

Agonistic CD40 antibody therapy induces tertiary lymphoid structures but impairs the response to immune checkpoint blockade in glioma

L. van Hooren, A. Vaccaro, M. Ramachandran, K. Vazaios, S. Libard, T. van de Walle, M. Georganaki, H. Huang, I. Pietilä, J. Lau, M. H. Ulvmar, M. C. Karlsson, M. Zetterling, S. M. Mangsbo, A. S. Jakola, , A. Dimberg

This study shows that agonistic CD40 antibody therapy in glioma models causes T cell dysfunction and reduces response to checkpoint inhibitors, but also promotes tertiary lymphoid structures associated with improved T cell infiltration.

bioRxiv · Jan 5, 2021Cancer Biology