Spheroplast-mediated carbapenem tolerance in Gram-negative pathogens
T. Cross, B. Ransegnola, J.-H. Shin, A. Weaver, K. Fauntleroy, M. VanNieuwenhze, L. Westblade, T. Dörr
This study shows that several Gram-negative pathogens exhibit carbapenem tolerance through cell wall-deficient spheroplasts, which can recover upon antibiotic removal.
bioRxiv · Mar 15, 2019Microbiology