BiophysicsbioRxiv
Arrhythmia-associated Calmodulin Variants Interact with KCNQ1 to Confer Aberrant Membrane Trafficking and Function
P. w. Kang, L. Woodbury, P. Angsutararux…·J. R. Silva
This study investigates how arrhythmia-associated calmodulin variants affect KCNQ1 binding, membrane trafficking, and function, revealing variable impacts on cardiac ion channel regulation.
DOI 10.1093/pnasnexus/pgad335