Regenerative hallmarks of aging: Insights through the lens of Pleurodeles waltl
Georgios Tsissios, Gabriella Theodoroudis-Rapp, Weihao Chen, Anthony Sallese, Byran J. Smucker, Lake Ernst, Junfan Chen, Yiqi Xu, Sophia C. Ratvasky, Hui Wang, Katia Del Rio‐Tsonis
This study examines age-related changes in lens regeneration in newts, finding that while regenerative capacity persists, aging slows the regeneration kinetics due to delayed cell cycle re-entry and ECM clearance.
bioRxiv · Sep 13, 2022 · PreprintDevelopmental Biology