Development of antibody-drug conjugates targeting L1CAM to treat metastatic cancer
Jin Suk Park, Carson Kenum, Lan Ying He, Abdul G. Khan, Mary Ann Pohl, Thomas E. White, Sreekumar R. Kodangattil, Charles M. Rudin, Paul J. Balderes, Ivo C. Lorenz, Joan Massagué, Karuna Ganesh
This paper develops antibody-drug conjugates targeting L1CAM to treat metastatic cancer, showing potent tumor control and extended survival in mouse models.
Molecular Cancer Therapeutics · Jan 8, 2026Peer-reviewedCancer Biology