Epigenetic signature and key transcriptional regulators of human antigen-specific type 1 regulatory T cells
Alma-Martina Cepika, Laura Amaya, Colin Waichler, Mansi Narula, Michelle M. Mantilla, Benjamin C. Thomas, Pauline P. Chen, Robert Arthur Freeborn, Mara Pavel-Dinu, Jason Nideffer, Matthew Porteus, Rosa Bacchetta, Fabian Müller, William J. Greenleaf, Howard Y. Chang, Maria Grazia Roncarolo
This study identifies the epigenetic signature and key transcription factors regulating human antigen-specific Tr1 cells, revealing their unique biology and potential for therapeutic applications.
bioRxiv · Mar 7, 2024 · PreprintImmunology