Structural insights into DHODH-mediated catalysis and drug resistance
Ruchika Pokhriyal, Hyuk‐Soo Seo, Mio Murakoso, S Trojan, LAURA EVANS, Jillian K. O'Neil, K. N. K. Chauhan, Shakchhi Joshi, Hanna Meyer, Anders Friberg, Judith Günther, SVEN GIESE, Sven Christian, Xiaoping Yang, Robert E. Lintner, , Julie-Aurore Losman
This study provides structural insights into DHODH catalysis and drug resistance by analyzing conformational changes and resistance mutations.
bioRxiv · Sep 24, 2026 · PreprintBiochemistry