Author

Judith Guenther

Bayer (Germany)ORCID 0000-0001-5794-8984Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Biochemistry· 2 Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Research Focus:batch correction / integration· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Organism:human· 1 Assay:imaging· 1

Frequent Co-Authors

David E. RootiD· 2 shared A.M. EdwardsiD· 1 shared Adriana BorowaiD· 1 shared Aiping DongiD· 1 shared Akhila MettuiD· 1 shared Albina Bolotokova· 1 shared Aleksandra IvanováiD· 1 shared Alexander FürlliD· 1 shared

Activity by Year

2023-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiochemistry

David E. RootORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintSep 24, 2026

Structural insights into DHODH-mediated catalysis and drug resistance

Ruchika Pokhriyal, Hyuk‐Soo Seo, Mio Murakoso…·Julie-Aurore Losman

This study provides structural insights into DHODH catalysis and drug resistance by analyzing conformational changes and resistance mutations.

DOI 10.64898/2026.09.23.753858

protein structureexperimental assay

𝕏 PostBluesky

BiochemistryJournal of Chemical Information and ModelingPeer-reviewedNov 5, 2024

CACHE Challenge #1: targeting the WDR domain of LRRK2, a Parkinson's Disease associated protein.

Fengling Li, Suzanne Z. Ackloo, C. H. Arrowsmith…·Matthieu Schapira

The paper evaluates computational hit-finding methods for targeting the WDR domain of LRRK2, a Parkinson's disease protein, finding that diverse strategies yielded weakly potent compounds.

34 citationstop 4%

deep learningdrug response / drug discovery

𝕏 PostBluesky

BioinformaticsbioRxivPreprintMar 23, 2023

✦ In-depth digest

JUMP Cell Painting chemical dataset: Morphological map of 115,796 compounds in human cells

Srinivas Niranj Chandrasekaran, Jeanelle Ackerman, Eric Alix…·Anne Elizabeth Carpenter

Cell Painting images and profiles for 115,796 compounds in U2OS cells from 12 laboratories; 15.2% of analyzed compounds are phenotypically active, and cross-laboratory replicates cut reference-compound activity by 34%.

98 citations

𝕏 PostBluesky