Poly(ADP-ribose) induces α-synuclein aggregation in neuronal-like cells andinteracts with phosphorylated α-synuclein in post mortem PD samples
Laura N. Puentes, Zsofia Lengyel‐Zhand, Ji Youn Lee, Chia‐Ju Hsieh, Mark E. Schneider, Kimberly J. Edwards, Kelvin C. Luk, Virginia M.‐Y. Lee, John Q. Trojanowski, Robert H. Mach
This study shows that PAR promotes α-synuclein aggregation and interacts with phosphorylated α-synuclein in Parkinson's disease samples.
bioRxiv · Apr 8, 2020 · PreprintNeuroscience