ROStrace detects oxidative stress in vivo and predicts progression of Alzheimer's disease pathology in APP/PS1 mice.
Chia‐Ju Hsieh, Catherine Hou, Yi Zhu, Ji Youn Lee, Neha Kohli, Evan P. Gallagher, Kuiying Xu, Hsiaoju S. Lee, Shihong Li, Meagan J. McManus, Robert H. Mach
This paper demonstrates that [18F]ROStrace PET imaging detects oxidative stress in APP/PS1 mice and correlates with amyloid burden, predicting Alzheimer's disease progression.
EJNMMI Research · Jul 27, 2022Peer-reviewedNeuroscience