EpCAM sustains crypt mechanics and prevents aberrant remodeling
Matis Soleilhac, Laura Ruiz, Dominique D. Berrebi, Amlan Barai, Brice Lecouffe, Sylvie Richelme, Valentine Obino, Tien Dang, Nicolas Buzhinsky, Félix Rico, Julie Salomon, Frank M. Ruemmele, Delphine Delacour
This study identifies EpCAM as a key regulator of epithelial contractility and crypt morphogenesis, showing its role in maintaining crypt structure and preventing aberrant remodeling.
bioRxiv · Apr 30, 2026 · PreprintDevelopmental Biology