Author

Laura Shapiro-Kulnane

Case Western Reserve University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Developmental Biology· 2 Genetics· 1

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Research Focus:differential expression· 3 Organism:Drosophila· 3 Research Focus:gene regulatory network inference· 3 Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1

Frequent Co-Authors

Helen K. SalziD· 3 shared Anne E. SmolkoiD· 2 shared Micah Selengut· 1 shared

Activity by Year

2018-2022 · peak 1/yr

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3 top collaborators · 2 mutual co-author links

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3 shared papersDevelopmental Biology

Helen K. SalzORCID

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3 papers

Recent·Most cited

Safeguarding Drosophila female germ cell identity depends on an H3K9me3 mini domain guided by a ZAD zinc finger protein

Laura Shapiro-Kulnane, Micah Selengut, Helen K. Salz

The paper identifies IDC, a ZAD zinc finger protein, as essential for H3K9me3 deposition at the phf7 gene in Drosophila female germ cells, preventing ectopic PHF7 expression.

PLoS Genetics · Dec 22, 2022Peer-reviewedGenetics

An autoregulatory switch in sex-specific phf7 transcription causes loss of sexual identity and tumors in the Drosophila female germline

Anne E. Smolko, Laura Shapiro-Kulnane, Helen K. Salz

This study shows that ectopic PHF7 in Drosophila female germ cells causes loss of sexual identity and tumor formation through autoregulatory transcriptional reprogramming.

Development · Jan 1, 2020Peer-reviewedDevelopmental Biology

The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells by repressing expression of key spermatogenesis genes

Anne E. Smolko, Laura Shapiro-Kulnane, Helen K. Salz

The paper shows SETDB1 maintains female germ cell identity in Drosophila by repressing spermatogenesis genes through H3K9me3 deposition, independent of its role in piRNA silencing.

Nature Communications · Oct 2, 2018Peer-reviewedDevelopmental Biology