Author

Anne E. Smolko

Case Western Reserve UniversityORCID 0000-0002-1247-4364Unclaimed ORCID profile · follow to get notified of new preprints

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Developmental Biology· 2

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Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:Drosophila· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:ChIP-seq· 1 Approach:experimental assay· 1

Frequent Co-Authors

Helen K. SalziD· 2 shared Laura Shapiro-Kulnane· 2 shared

Activity by Year

2018-2020 · peak 1/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersDevelopmental Biology

Helen K. SalzORCID

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2 papers

Recent·Most cited

Developmental BiologyDevelopmentPeer-reviewedJan 1, 2020

An autoregulatory switch in sex-specific phf7 transcription causes loss of sexual identity and tumors in the Drosophila female germline

Anne E. Smolko, Laura Shapiro-Kulnane, Helen K. Salz

This study shows that ectopic PHF7 in Drosophila female germ cells causes loss of sexual identity and tumor formation through autoregulatory transcriptional reprogramming.

10 citations

Drosophilabulk RNA-seq

𝕏 PostBluesky

Developmental BiologyNature CommunicationsPeer-reviewedOct 2, 2018

The H3K9 methyltransferase SETDB1 maintains female identity in Drosophila germ cells by repressing expression of key spermatogenesis genes

Anne E. Smolko, Laura Shapiro-Kulnane, Helen K. Salz

The paper shows SETDB1 maintains female germ cell identity in Drosophila by repressing spermatogenesis genes through H3K9me3 deposition, independent of its role in piRNA silencing.

52 citations

DrosophilaChIP-seq

𝕏 PostBluesky