Directional predictions of HIV transmission with optimised genomics in cohorts of serodiscordant couples
Lele Zhao, Matthew D. Hall, Chris Wymant, Lucie Abeler‐Dörner, Newton Otieno Otecko, George MacIntyre-Cockett, Sandra E Chaudron, Laura Thomson, Tanya Golubchik, Jairam R. Lingappa, Luca Ferretti A, Katrina Lythgoe, Christophe Fraser, Joshua T. Herbeck, David Bonsall
The paper evaluates two tools for HIV transmission direction prediction using short and long-read sequencing data from serodiscordant couples, showing long reads improve phylogenetic resolution and transmission prediction accuracy.
bioRxiv · Oct 19, 2023 · PreprintGenomics