Author

Laura V. Sparsoe

Aarhus University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

Helle A. PrætoriusiD· 2 shared Mette G. ChristenseniD· 2 shared Nanna JohnseniD· 2 shared Thomas J. CorydoniD· 2 shared Emil H LambertseniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersPhysiology

Helle A. PrætoriusORCID

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2 papers

Recent·Most cited

P2Y2 receptors are essential for hepatic clearance ofuropathogenic E. coli in a murine sepsis model

Mette G. Christensen, Nanna Johnsen, Laura V. Sparsoe, Thomas J. Corydon, Helle A. Prætorius

This study shows that P2Y2 receptors are essential for hepatic clearance of uropathogenic E. coli, leading to improved survival in a murine sepsis model.

bioRxiv · Jun 10, 2025 · PreprintPhysiology

Platelet-dependent clearance of uropathogenic Escherichia coli directly drives sepsis-induced thrombocytopenia in a mouse model

Nanna Johnsen, Mette G. Christensen, Laura V. Sparsoe, Emil H Lambertsen, Thomas J. Corydon, Helle A. Prætorius

This study shows that platelets clear uropathogenic E. coli in a mouse model, leading to thrombocytopenia during sepsis.

bioRxiv · May 23, 2025 · PreprintPhysiology