Author

Helle A. Prætorius

Aarhus UniversityORCID 0000-0002-0970-5061Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2

Frequent Co-Authors

Laura V. Sparsoe· 2 shared Mette G. ChristenseniD· 2 shared Nanna JohnseniD· 2 shared Thomas J. CorydoniD· 2 shared Emil H LambertseniD· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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2 shared papersPhysiology

Laura V. Sparsoe

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2 papers

Recent·Most cited

PhysiologybioRxivPreprintJun 10, 2025

P2Y2 receptors are essential for hepatic clearance ofuropathogenic E. coli in a murine sepsis model

Mette G. Christensen, Nanna Johnsen, Laura V. Sparsoe…·Helle A. Prætorius

This study shows that P2Y2 receptors are essential for hepatic clearance of uropathogenic E. coli, leading to improved survival in a murine sepsis model.

DOI 10.1101/2025.06.10.658777

mouseexperimental assay

𝕏 PostBluesky

PhysiologybioRxivPreprintMay 23, 2025

Platelet-dependent clearance of uropathogenic Escherichia coli directly drives sepsis-induced thrombocytopenia in a mouse model

Nanna Johnsen, Mette G. Christensen, Laura V. Sparsoe…·Helle A. Prætorius

This study shows that platelets clear uropathogenic E. coli in a mouse model, leading to thrombocytopenia during sepsis.

1 citation

mouseexperimental assay

𝕏 PostBluesky