Loss of ninein interferes with osteoclast formation and causes premature ossification
Thierry Gilbert, Camille Gorlt, Merlin Barbier, Benjamin Duployer, Marianna Plozza, Ophélie Dufrançais, Laure-Elene Martet, Elisa Dalbard, Loelia Segot, Christophe Tenailleau, Laurence Haren, Christel Vérollet, Christiane Bierkamp, Andreas Merdes
This study shows that ninein deficiency impairs osteoclast formation and bone resorption, leading to premature ossification and altered skeletal development.
eLife · Jun 5, 2024Peer-reviewedDevelopmental Biology