Author

Lauren Gurski

Regeneron (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Genetic & Genomic Medicine· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Approach:statistical model· 4 Research Focus:GWAS / association mapping· 3 Assay:GWAS summary statistics· 3 Research Focus:benchmarking· 1 Research Focus:software / tool· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1

Frequent Co-Authors

Adam J. Mansfield· 3 shared Alan R. ShuldineriD· 3 shared Alexander E. LopeziD· 3 shared Alicia C. Hawes· 3 shared Andrew Deubler· 3 shared Anthony MarckettaiD· 3 shared Arden MoscatiiD· 3 shared Arkopravo GhoshiD· 3 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenetic & Genomic Medicine

Adam J. Mansfield

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Genomic ascertainment of CHEK2-related cancer predisposition

Sun Young Kim, Jung Kim, Mark Ramos, Jeremy S. Haley, Diane T. Smelser, H. Shanker Rao, Uyenlinh L. Mirshahi, Katherine L. Nathanson, Barry I. Graubard, Hormuzd A. Katki, David J. Carey, Douglas R. Stewart, Aris Baras, Gonçalo R. Abecasis, Adolfo A. Ferrando, , Arden Moscati

This study quantifies cancer risk and penetrance in CHEK2 heterozygotes using genomic data from two large biobanks, finding increased risks for several cancers and younger age of onset.

JAMA Network Open · Dec 15, 2025Peer-reviewedGenetic & Genomic Medicine

Computationally efficient meta-analysis of gene-based tests using summary statistics in large-scale genetic studies

Tyler Joseph, Joelle S. Mbatchou, Arkopravo Ghosh, Anthony Marcketta, Christopher E. Gillies, Jing Tang, Priyanka Nakka, Xinyuan Zhang, Jack A. Kosmicki, Carlo Sidore, Lauren Gurski, Maya Ghoussaini, Manuel A. R. Ferreira, Gonçalo R. Abecasis, Jonathan Marchini

The paper introduces REMETA, a tool for efficiently performing meta-analysis of gene-based tests using summary statistics, demonstrating its application on UK Biobank data.

Nature Genetics · Nov 12, 2025Peer-reviewedGenetic & Genomic Medicine

Population-scale analysis of common and rare genetic variation associated with hearing loss in adults

Kavita Praveen, Lee Dobbyn, Lauren Gurski, Ariane H. Ayer, Jeffrey C. Staples, Shawn Mishra, Yu Bai, Alexandra M. Kaufman, Arden Moscati, Christian Benner, Esteban Chen, Siying Chen, Alexander Popov, Janell Smith, Lance J. Adams, , Joe Burns

This study identifies 53 genetic loci associated with hearing loss, including 15 novel ones, using genome-wide and exome-sequencing data from multiple cohorts.

Communications Biology · Jun 3, 2022Peer-reviewedGenetic & Genomic Medicine

Genome-wide analysis in 756,646 individuals provides first genetic evidence that ACE2 expression influences COVID-19 risk and yields genetic risk scores predictive of severe disease

Julie E. Horowitz, Jack A. Kosmicki, Amy Damask, Deepika Sharma, Genevieve H. L. Roberts, Anne E. Justice, Nilanjana Banerjee, Marie V. Coignet, Ashish Yadav, Joseph B. Leader, Anthony Marcketta, Danny S. Park, Rouel Lanche, Evan K. Maxwell, Spencer C. Knight, , Arden Moscati

The paper identifies a rare variant that lowers ACE2 expression and reduces COVID-19 risk, and develops a genetic risk score predicting severe disease.

Nature Genetics · Mar 3, 2022Peer-reviewedGenetic & Genomic Medicine