Cancer BiologybioRxivPreprint
A second generation IL-2 receptor-targeted diphtheria fusion toxin exhibits anti-tumor activity and synergy with anti-PD-1 in melanoma
Laurene S. Cheung, Juan Fu, Pankaj Kumar…·William R. Bishai
This paper describes a second-generation diphtheria toxin-based fusion protein with reduced vascular leak and improved therapeutic activity in melanoma when used alone or with anti-PD-1.
DOI 10.1101/420158