Oligodendrocytes depend on MCL-1 to prevent spontaneous apoptosis and white matter degeneration
Abigail H. Cleveland, Alejandra I. Romero-Morales, Laurent Alfonso Azcona, Melisa Herrero, Viktoriya D. Nikolova, Sheryl S. Moy, Orna Elroy‐Stein, Vivian Gama, Timothy R. Gershon
This study shows that oligodendrocytes require MCL-1 to prevent apoptosis and white matter degeneration, suggesting MCL-1 deficiency contributes to leukodystrophy.
Cell Death and Disease · Dec 6, 2021Peer-reviewedNeuroscience