Sheryl S. Moy

This study shows that proinflammatory microglia contribute to neuronal death and hyperkatifeia during prolonged abstinence from binge alcohol in mice.

This study identifies neuronal lysosomal acid lipase (LAL) loss as a driver of amyloid pathology in Alzheimer's disease by linking disrupted lipophagy to Aβ accumulation and cognitive deficits.

The paper identifies the development of a gut-brain circuit involving entero-endocrine cells and vagal neurons, showing its role in feeding and social behavior through BDNF regulation.

This study investigates the distinct roles of perineuronal nets on CA2 pyramidal cells and parvalbumin-expressing cells in hippocampal-dependent memory using conditional knockout mice.

This study identifies ASD-like transcriptomic changes in oligodendrocytes and microglia of C58/J mice amygdala, dependent on sex and sociability, using bulk RNA-Seq and snRNA-Seq.

The paper investigates how social threat alters behavioral structure and reshapes functional brain connectivity in mice through behavioral tracking and inter-regional correlation analysis.

This study shows that sleep disruption accelerates cognitive decline in male P301S Tau mice but not females, without directly causing synaptic Tau pathology.

This study shows that loss of GABA co-transmission from cholinergic neurons in mice leads to deficits in social, spatial, and fear memory, and altered behavior strategies.

This study shows that oligodendrocytes require MCL-1 to prevent apoptosis and white matter degeneration, suggesting MCL-1 deficiency contributes to leukodystrophy.

The paper introduces MiniMUGA, a genotyping array for mouse genetic QC, showing it effectively discriminates strains, detects genetic constructs, and identifies sex chromosome abnormalities.

This study shows that a brain-specific PGC1α isoform mutation causes motor deficits and gene upregulation in female mice, suggesting a role in female-specific transcriptional programs.

This study shows that TRIM67 is critical for brain development and behavior, with deletion causing anatomical and functional impairments in mice.

This study investigates the role of CA2 pyramidal neurons in hippocampal oscillations and social behavior using DREADDs in mice, finding bidirectional regulation of low gamma oscillations and impaired social approach with inhibition.