Cellular adaptation of mitochondrial metabolism and biogenesis in response to partial ATP synthase uncoupling
Elodie Sardin, François Godard, Jean-Paul Lasserre, Bénédicte Salin, Laurianne Daniel, Jenny Renaut, Jean‐Paul di Rago, Stéphane Duvezin‐Caubet, Emmanuel Tétaud
This paper investigates how partial mitochondrial uncoupling in yeast affects mitochondrial biogenesis, metabolism, and structure, revealing reversible adaptations linked to the proton-motive force.
bioRxiv · Dec 19, 2025 · PreprintMolecular Biology