Author

Giuseppina Giglia‐Mari

Lyon 1 UniversitéORCID 0000-0003-2001-1965Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1 Research Focus:gene regulatory network inference· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Lise‐Marie DonnioiD· 4 shared Charlène MagnaniiD· 3 shared Pierre‐Olivier MariiD· 3 shared Damien NeuilletiD· 2 shared Elena CeruttiiD· 2 shared Amélie ZachayusiD· 1 shared Arnaud JacquieriD· 1 shared Cathy Braun· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersMolecular Biology

Lise‐Marie DonnioORCID

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4 papers

Recent·Most cited

Nucleolar reorganization after cellular stress is orchestrated by SMN shuttling between nuclear compartments

Shaqraa Musawi, Lise‐Marie Donnio, Zehui Zhao, Charlène Magnani, Phoebe Rassinoux, Olivier Binda, Jianbo Huang, Arnaud Jacquier, Laurent Coudert, Patrick Lomonte, Cécile Martinat, Laurent Schaeffer, Denis Mottet, Jocelyn Côté, Pierre‐Olivier Mari, Giuseppina Giglia‐Mari

The paper shows that SMN shuttles from Cajal bodies to the nucleolus during DNA repair, aiding in nucleolar structure restoration after genotoxic stress.

Nature Communications · Nov 15, 2023Peer-reviewedMolecular Biology

Active mRNA degradation by EXD2 nuclease elicits recovery of transcription after genotoxic stress

Jérémy Sandoz, Max Cigrang, Amélie Zachayus, Philippe Catez, Lise‐Marie Donnio, Clémence Elly, Jadwiga Nieminuszczy, Pietro Berico, Cathy Braun, Sergey Alekseev, Jean‐Marc Egly, Wojciech Niedźwiedź, Giuseppina Giglia‐Mari, Emmanuel Compe, Frédéric Coin

The paper shows that EXD2 nuclease degrades nascent mRNAs during genotoxic stress, enabling transcription recovery after DNA repair.

Nature Communications · Jan 20, 2023Peer-reviewedMolecular Biology

XAB2 Dynamics during DNA Damage-Dependent Transcription Inhibition

Lise‐Marie Donnio, Elena Cerutti, Charlène Magnani, Damien Neuillet, Pierre‐Olivier Mari, Giuseppina Giglia‐Mari

This study investigates XAB2's role in Transcription-Coupled NER, showing it is remobilized after DNA damage and detached from R-loops and repair proteins.

eLife · Jul 26, 2022Peer-reviewedMolecular Biology

β-Actin and Nuclear Myosin I are responsible for nucleolar reorganization during DNA Repair.

Elena Cerutti, Laurianne Daniel, Lise‐Marie Donnio, Damien Neuillet, Charlène Magnani, Pierre‐Olivier Mari, Giuseppina Giglia‐Mari

This study identifies Nuclear Myosin I and Nuclear Beta Actin as essential for reorganizing the nucleolus after DNA repair by coordinating the displacement and re-entry of rDNA/RNAP1.

bioRxiv · May 22, 2019 · PreprintMolecular Biology