Author

Leda Liko

Oregon State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Assay:electronic health records· 1 Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Alejandro Z. Bihun· 1 shared Alexandra Hoff· 1 shared Amanda Kelley· 1 shared Arpa EbrahimiiD· 1 shared Ashley Hoff· 1 shared Benjamin Hagen· 1 shared Claudia S. MaieriD· 1 shared Duncan MacMurchy· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Alejandro Z. Bihun

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1 paper

Recent·Most cited

Appearance of Amyloid-β Early in Life Initiates Neuronal Hyper-excitability, Mitochondrial Decay, and Loss of Dendritic Complexity in the Hippocampal CA1 Region of 5xFAD Mice

Amanda Kelley, Emily Denise Sackinger, Mathew Frischman, Nicholas O. Thomas, Kaitlyn Kim, Grace Scuderi, Edwin M. Labut, Duncan MacMurchy, Toren Ikea-Mario, Jacob Rauenhorst, Easton Neitzel, Tacita Vu, Leda Liko, Alexandra Hoff, Ashley Hoff, , Tory M. Hagen

This study identifies early synaptic and metabolic dysfunctions in 5xFAD mice before plaque formation, linking them to hippocampal vulnerability in Alzheimer's disease.

bioRxiv · Feb 6, 2026 · PreprintNeuroscience