Rapid and efficient in vivo astrocyte-to-neuron conversion with regional identity and connectivity?
Lei-Lei Wang, Carolina Serrano, Xiaoling Zhong, Shuaipeng Ma, Yuhua Zou, Chun‐Li Zhang
The paper shows that NEUROD1-induced neurons in the adult mouse brain originate from endogenous neurons, not astrocytes, highlighting the need for rigorous lineage tracing in reprogramming studies.
Cell · Sep 27, 2021Peer-reviewedNeuroscience