Author

Yuhua Zou

The University of Texas Southwestern Medical Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Chun‐Li ZhangiD· 4 shared Shuaipeng MaiD· 2 shared Wenjiao Tai· 2 shared Xiaoling ZhongiD· 2 shared Bo CheniD· 1 shared Carolina SerranoiD· 1 shared Haoqi NiiD· 1 shared Jingcheng wang· 1 shared

Activity by Year

2021-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersNeuroscience

Chun‐Li ZhangORCID

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4 papers

Recent·Most cited

Phosphorylation and DNA Damage Resolution Coordinate SOX2-Mediated Reprogramming in vivo

Xiaoling Zhong, Yuhua Zou, Chun‐Li Zhang

This study shows that SOX2 phosphorylation and the PRKDC-dependent NHEJ pathway are essential for in vivo glia-to-neuron reprogramming, with p53 knockdown restoring reprogramming in PRKDC-deficient mice.

Proceedings of the National Academy of Sciences · Mar 17, 2026Peer-reviewedNeuroscience

in vivo Reprogramming of NG2 Glia Improves Bladder Function After Spinal Cord Injury

Wenjiao Tai, Junkui Shang, Peiqi Zhao, Wei Li, Tianjin Shen, Xiaoling Zhong, Yuhua Zou, Bo Chen, Chun‐Li Zhang

This study shows that reprogramming NG2 glia with SOX2 improves bladder function in a mouse model of spinal cord injury by promoting neurogenesis and reducing glial scarring.

iScience · Jan 30, 2026Peer-reviewedNeuroscience

Chemical screens in aging-relevant human motor neurons identify MAP4Ks as therapeutic targets for amyotrophic lateral sclerosis

Menglu Liu, Shuaipeng Ma, Wenjiao Tai, Xiaoling Zhong, Haoqi Ni, Yuhua Zou, Jingcheng wang, Chun‐Li Zhang

The paper identifies MAP4Ks as therapeutic targets for ALS by screening chemical compounds in human motor neurons and shows a lead compound improves neuron survival and function.

bioRxiv · Apr 24, 2023 · PreprintNeuroscience

Rapid and efficient in vivo astrocyte-to-neuron conversion with regional identity and connectivity?

Lei-Lei Wang, Carolina Serrano, Xiaoling Zhong, Shuaipeng Ma, Yuhua Zou, Chun‐Li Zhang

The paper shows that NEUROD1-induced neurons in the adult mouse brain originate from endogenous neurons, not astrocytes, highlighting the need for rigorous lineage tracing in reprogramming studies.

Cell · Sep 27, 2021Peer-reviewedNeuroscience