Early and Delayed STAT1-Dependent Responses Drive Local Trained Immunity of Macrophages in the Spleen
Aryeh Solomon, Noa Bossel Ben Moshe, Dotan Hoffman, Sébastien Trzebanski, Dror Yehezkel, Leia Vainman, Mihai Gheorghe Netea, Roi Avraham
This study identifies early and delayed STAT1-dependent responses in splenic macrophages that drive trained immunity, enhancing protection against Salmonella Typhimurium infection.
eLife · Oct 7, 2024Peer-reviewedImmunology