Author

Lena Jaschkowitz

German Center for Neurodegenerative Diseases

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Aida Cardona‐AlberichiD· 1 shared Andreas J. Huber· 1 shared Christian BehrendsiD· 1 shared Francesco GubinelliiD· 1 shared Lena F. BurbullaiD· 1 shared Leonie M. Heger· 1 shared Martina SchiffereriD· 1 shared Matteo RovereiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Aida Cardona‐AlberichORCID

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1 paper

Recent·Most cited

VMAT2 dysfunction impairs vesicular dopamine uptake, driving its oxidation and α-synuclein pathology in DJ-1-linked Parkinson's disease neurons

Leonie M. Heger, Francesco Gubinelli, Andreas J. Huber, Aida Cardona‐Alberich, Matteo Rovere, Ulf Matti, Stephan A. Müller, Sankarshana R. Nagaraja, Lena Jaschkowitz, Martina Schifferer, Wolfgang Wurst, Stefan F. Lichtenthaler, Christian Behrends, Sivakumar Sambandan, Lena F. Burbulla

This study shows that DJ-1 deficiency impairs VMAT2 function and vesicle dynamics, leading to dopamine oxidation and α-synuclein pathology in Parkinson's disease neurons.

Science Advances · Feb 11, 2026Peer-reviewedNeuroscience