The Molecular Determinants of a Universal Prion Acceptor
Hamza Arshad, Zeel Patel, Zaid A.M. Al‐Azzawi, Leyao Li, Genki Amano, Surabhi Mehra, Shehab Eid, Gerold Schmitt‐Ulms, Joel C. Watts
The paper identifies key amino acid residues in bank vole prion protein (BVPrP) that enable it to act as a universal prion acceptor, revealing molecular mechanisms for cross-species prion replication.
PLoS Pathogens · Sep 10, 2024Peer-reviewedNeuroscience