NeurosciencebioRxivPreprint
The Protein Disulfide Isomerase P4HB/PDIA1 Modulates PrPC Levels and Prion Replication
Genki Amano, Hamza Arshad, Zeel Patel…·Joel C. Watts
This study shows that P4HB/PDIA1 modulates PrPC levels and prion replication by stabilizing PrPC and acting as a chaperone in CAD5 cells.
DOI 10.64898/2025.12.01.691611