Coupling Stickland fermentation with reverse β-oxidation represents a new mode of medium-chain carboxylate production
Blake G. Lindner, Dinesh Kumar Nallasamy, Liam Roberts, Ian Mateus Gois, Christopher E. Lawson
This study identifies a novel metabolic pathway in chain elongating bacteria that couples Stickland fermentation with reverse β-oxidation to produce medium-chain carboxylic acids.
bioRxiv · Sep 30, 2026 · PreprintMicrobiology