Circulating APOH promotes aortic dissection by activating the vascular smooth muscle cell NR5A1-PPARγ pathway.
Likang Ma, lei jin, Juncheng Liu, Li J, Maolin Liu, Le Chen, Zhihuang Qiu
This study identifies APOH as a promoter of aortic dissection by activating the NR5A1-PPARγ pathway in vascular smooth muscle cells, leading to phenotypic switching and inflammation.
bioRxiv · Jul 23, 2026 · PreprintGenomics