SETD2 deficiency promotes renal fibrosis through the TGF-β/Smad signaling pathway in the absence of VHL
Changwei Liu, Xiaoxue Li, Yiwen Zhu, Wenxin Feng, Wei Zhang, Chunxiao Ma, Yue Xu, Liming Gui, Rebiguli Aji, Wei‐Qiang Gao, Li Li
This study shows that SETD2 deficiency promotes renal fibrosis by activating the TGF-β/Smad signaling pathway in VHL-deficient mice.
bioRxiv · Sep 10, 2022 · PreprintMolecular Biology