Author

Yue Xu

Shanghai Jiao Tong University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cancer Biology· 2 Cell Biology· 2 Neuroscience· 2 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:mouse· 5 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Assay:ChIP-seq· 2 Approach:genetic perturbation / CRISPR· 2

Frequent Co-Authors

Rebiguli Aji· 4 shared Wei‐Qiang GaoiD· 4 shared Wenxin Feng· 4 shared Hanyu RaoiD· 3 shared Ningyuan LiuiD· 3 shared Changwei LiuiD· 2 shared Dehuan Wang· 2 shared Li LiiD· 2 shared

Activity by Year

2022-2026 · peak 4/yr

Co-Author Collaboration Network

10 top collaborators · 34 mutual co-author links

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4 shared papersCell Biology

Rebiguli Aji

Mutual co-authors in cluster

Author profile →

7 papers

Recent·Most cited

Brain state locks silent memories in a trained fly connectome

Han Wang, Joe Poh Sheng YEONG, Yunhua Zhao, Yuhui Zhao, Zizhong Yu, Xiaoyu Liu, Ruoyun He, Huikuan Chen, Ting Liu, Ye Tian, Weibang Chen, Yao Cai, Yue Xu, Hongyu Ning, Xuanhe Hou, , Chunjie Tian

The paper demonstrates that a fixed neural wiring diagram in Drosophila can store and retrieve memories through neuronal adaptation, dependent on specific brain states.

bioRxiv · Oct 29, 2026 · PreprintNeuroscience

Longitudinal Awake Mouse Brain Imaging Using Functional Ultrasound and Functional Ultrasound Localization Microscopy

Zhe Huang, Yike Wang, Matthew R. Lowerison, Yue Xu, Murong Yi, Bing‐Ze Lin, YiRang Shin, Nathiya Vaithiyalingam Chandra Sekaran, Daniel A. Llano, Pengfei Song

This study establishes and validates an awake longitudinal fUS-ULM-fULM framework in mice over five months, showing no significant longitudinal drift and no memory impairment or chronic neuroinflammation.

Advanced Science · Sep 27, 2026Peer-reviewedNeuroscience

NSD2 deficiency disrupts the epigenetic landscape of cochlear hair cells to enhance ECM expression and to perturb cochlear hair cell function

Ziyi Wang, Yue Xu, Xiaojie Ma, Dehuan Wang, Wenxin Feng, Ningyuan Liu, Hanyu Rao, Wei Zhang, Rebiguli Aji, Ziwen Yu, Jiahe Li, Guoning Yu, Yazhi Xing, Wei‐Qiang Gao, Li Li

This study shows that NSD2 deficiency disrupts chromatin accessibility and gene expression in cochlear hair cells, leading to increased ECM expression and hearing impairment, which can be mitigated by ECM intervention.

bioRxiv · Sep 23, 2026 · PreprintCell Biology

Oxidized protein states define metastatic fitness in lung cancer

Maolin Ge, Magdy Gohar, Consuelo Torrini, Yukako Suzuki, Jiang, Yuchen Huang, Benjamin Weinstein, Janice Wong, Naema Nayyar, Md Yousuf Ali, Emily Sullivan, Stefan Andrew Harry, Çağrı Çakici, Zhuanglin Dai, Nicolò Vivori, , Liron Bar‐Peled

The paper identifies oxidative protein states as drivers of metastatic fitness in lung cancer by linking ROS-regulated protein modifications to mitochondrial function and metastasis.

bioRxiv · Jul 19, 2026 · PreprintCancer Biology

NSD2 promotes cell durotaxis and drives the transition from PKD to tubulocystic renal cell carcinoma through integrin/FAK/AKT signaling

Wenxin Feng, Ningyuan Liu, Changwei Liu, Hanyu Rao, Zhuo Chen, Wei Zhang, Yue Xu, Rebiguli Aji, Ziyi Wang, Wei‐Qiang Gao, Li Li

This study shows NSD2 promotes cell durotaxis and drives the transition from PKD to TCRCC via integrin/FAK/AKT signaling, with implications for targeted therapies.

Oncogene · Jul 22, 2025Peer-reviewedCancer Biology

Histone 3 lysine 36 trimethylation by SETD2 shapes an epigenetic landscape in intestinal stem cells to orchestrate lipid metabolism and prevent cell senescence.

Yue Xu, Ziyi Wang, Wenxin Feng, Hanyu Rao, Dehuan Wang, Wei Zhang, Rebiguli Aji, Ningyuan Liu, Wei‐Qiang Gao, Li Li

This study shows that H3K36me3, catalyzed by SETD2, maintains ISC stemness by regulating lipid metabolism and preventing senescence through chromatin remodeling and metabolic intervention.

bioRxiv · Apr 9, 2025 · PreprintCell Biology

SETD2 deficiency promotes renal fibrosis through the TGF-β/Smad signaling pathway in the absence of VHL

Changwei Liu, Xiaoxue Li, Yiwen Zhu, Wenxin Feng, Wei Zhang, Chunxiao Ma, Yue Xu, Liming Gui, Rebiguli Aji, Wei‐Qiang Gao, Li Li

This study shows that SETD2 deficiency promotes renal fibrosis by activating the TGF-β/Smad signaling pathway in VHL-deficient mice.

bioRxiv · Sep 10, 2022 · PreprintMolecular Biology