In Vivo Surface Reconstruction of Three Signal-defined Intracortical Layers Using 5T 3D FLAIR MR Imaging
Shui Cao, Lu Shi, Jiameng Liu, Zifeng Lian, Lin Teng, Qin Xiao, Xiaona Xia, Kaicong Sun, Feng Shi, Xiangshui Meng, Dinggang G. Shen
This paper develops BrainMLSR, an automated framework to reconstruct three intracortical signal-defined layers from 5T 3D FLAIR MRI, showing high agreement with manual annotations and revealing regional morphometric differences in epilepsy.
bioRxiv · Feb 9, 2026 · PreprintNeuroscience