Author

Lin Ye

National Institutes of Health

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Approach:machine learning (classical)· 1 Assay:proteomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Chaoyi Chen· 1 shared Hongchang Dong· 1 shared Honghui Lai· 1 shared Jialing LiiD· 1 shared Matthew D. HalliD· 1 shared Min SheniD· 1 shared Paul ShinniD· 1 shared Pei Xu· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Chaoyi Chen

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2 papers

Recent·Most cited

Sp100-HMG drives 'inside-out' PML-NB assembly to modulate transcription and cell-cycle dynamics

Hongchang Dong, Xiuyan Guo, Yilei Ma, Chaoyi Chen, Jialing Li, Xiaoli Zhang, Weidong Li, Xiaomei Deng, Honghui Lai, Yaotong Liao, Lin Ye, Pei Xu

This study identifies Sp100-HMG as a master liquid nucleator that drives 'inside-out' PML-NB assembly, modulating transcription and cell-cycle dynamics through hierarchical condensation.

bioRxiv · Jul 28, 2025 · PreprintCell Biology

A Comprehensive Collection of Pain and Opioid Use Disorder Compounds for High-Throughput Screening and Artificial Intelligence-Driven Drug Discovery

Xin Hu, Paul Shinn, Zina Itkin, Lin Ye, Ya-Qin Zhang, Min Shen, Stephanie L. Ford‐Scheimer, Matthew D. Hall

The paper creates a comprehensive small molecule library for pain and opioid use disorder with physical samples and an AI-driven platform for drug discovery.

ACS Pharmacology & Translational Science · Jul 22, 2024Peer-reviewedBioinformatics